A. L-carnitine is an amino acid derivative of L-lysine and L-methionine. It is synthesized in the human body, the majority made in the liver and kidneys. L-carnitine plays a role in cellular energy production and has some antioxidant activity.† It's responsible for the transport of long-chain fatty acids across the inner mitochondrial membranes into the mitochondria. It also removes short-chain and medium chain fatty acids from the mitochondria. L-carnitine supplementation is primarily indicated for use in carnitine deficiency. Acetyl-L-carnitine is one of the primary forms of L-carnitine, along with propionyl-L-carnitine. Acetyl-L-carnitine is able to cross the blood-brain barrier more efficiently than L-carnitine. Therefore, acetyl-L-carnitine provides neuroprotective benefits, including antioxidant activity, improved mitochondrial energetics, stabilization of intracellular membranes, cholinergic neurotransmission activity, and enhancement of brain growth factors known to naturally decline with age.†

A. Caution should be taken whenever recommending, or consuming, nutritional supplements. Use this drug-nutrient interaction checker to view potential interactions with the ingredients of Acetyl L-Carnitine.