Beneficial Bacteria Found to Support Vaginal Health

// Integrative Therapeutics


New findings in the European Journal of Obstetrics, Gynecology and Reproductive Biology reaffirm the role of probiotics in a woman’s urogenital health. Maintaining bacterial balance is important to vaginal health, however numerous factors, including hormonal changes, sexual activity, douching, stress, and diet can impact the homeostasis of microflora.†

At the end of the study, balanced vaginal microbiota was found in 61.5 percent of those in the probiotic gropucompared to 26.9 percent in the placebo group.

The study—which was a double-blind, randomized, placebo-controlled trial—involved 544 women. Subjects received either a probiotic containing a combination of Lactobacillus rhamnousus GR-1 and Lactobacillus reuteri RC-14 or placebo daily for six weeks. At the end of the study, balanced vaginal microbiota was found in 61.5% of those in the probiotic group compared to 26.9% in the women taking the placebo. † After an additional six weeks without supplementation, normal vaginal microbiotia were still present in 51.1% of the subjects who had been in the probiotic group compared to just 20.8% of women in the placebo group.†

Earlier research has shown that the oral administration of these two species of Lactobacillus support a healthy vaginal environment.†

This new clinical trial suggests that supplemental probiotics containing these two particular strains of Lactobacillus promote the colonization of beneficial microbiota and may help to support overall vaginal health.†


Reid G. Probiotic Lactobacilli for urogenital health in women. J Clin Gastroenterol. 2008;42 Suppl 3 Pt 2:S234-6.

Shopova E. Hydrogen peroxide-producing Lactobacillus species in healthy women and in women with bacterial vaginosis. Akush Ginekol (Sofiia). 2003;42 Suppl 1:12-5.

Vujic G, Jajac Knez A, Despot Stefanovic V, et al. Efficacy of orally applied probiotic capsules for bacterial vaginosis and other vaginal infections: a double-blind, randomized, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 2013 Feb 7 [Epub ahead of print].

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