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Heartburn Advantage™

Heartburn Advantage’s multi-mechanistic approach combines several clinically studied ingredients at researched doses to help reduce occasional heartburn, bloating, nausea, and epigastric discomfort.* The ingredients in Heartburn Advantage support the natural protective mechanisms in the gastrointestinal tract without interfering in the normal digestive process.*
Item #:

  • 12953 - Heartburn Advantage
  • 12953 - Heartburn Advantage
Suggested Retail Price (per unit)
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Count:  60 Capsules
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Heartburn Advantage's convenient dosing helps relieve occasional:

  • heartburn*
  • epigastric discomfort*
  • gastric discomfort*
  • bloating*
  • upset stomach*
  • indigestion*
  • nausea*


Supports gastrointestinal tissue health and gastric function, a healthy gastric balance of microflora, motility, and transport.*


PepZin GI® is a registered trademark of Hamari Chemicals USA, Inc.

Pycrinil® is a registered trademark of Indena SpA.

Gutgard® is a registered trademark of Natural Remedies LTD. exclusively distributed by AIDP in North America.

Features clinically-studied, practitioner-selected ingredients, including:

  • PepZinGI® brand Zinc-Carnosine, a novel patented crystalline chelate compound
  • A proprietary blend of standardized Pycrinil® artichoke (Cynara cardunculus) and ginger (Zingiber officinale) extracts
  • GutGard® DGL, a flavonoid extract of Glycyrrhiza glabra containing less than 1% glycyrrhizin

Clinical trials have demonstrated significant improvements in both objective outcomes and subjective measures during intervention periods with Zinc-Carnosine, showing endoscopically demonstrable effects within 4 to 8 weeks.* 1,2,3,4,5  Deglycyrrhizinated licorice (DGL) supports the production of mucin, a compound that coats and protects the digestive tract to provide relief for occasional stomach discomfort.* Heartburn Advantage ™ also contains a unique, well-tolerated, clinically-studied, prokinetic agent.*


1. Miyoshi A, Namiki M, Asagi S, et al. Jpn Pharmacol Ther. 1992 Jan 20;20(1):199–223.

2. Hayakawa A, Inoue M, Kunizaki M, et al. Jpn Pharmacol Ther. 1992 Jan 20;20(1): Offprint.

3. Suzuki Y, Kasanuki J, Yoshida H. Jpn Pharmacol Ther. 1992;20(1): Offprint.

4. Morise K, Oka Y, Suzuki T, et al. Jpn Pharmacol Ther. 1992;20(1);235–44.

5. Amakawa T. Jpn Pharmacol Ther. 1992;20(1):199–223.

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